首页> 外国专利> fusion protein, polynucleotide, vector, host cell, methods for producing fusion protein, treating a disease in an individual and for selective in vitro or in vivo activation of regulatory cells, pharmaceutical composition, use of fusion protein and invention .

fusion protein, polynucleotide, vector, host cell, methods for producing fusion protein, treating a disease in an individual and for selective in vitro or in vivo activation of regulatory cells, pharmaceutical composition, use of fusion protein and invention .

机译：融合蛋白，多核苷酸，载体，宿主细胞，产生融合蛋白，在个体中治疗疾病以及选择性地体外或体内激活调节细胞的方法，药物组合物，融合蛋白的用途和发明。

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摘要

The present invention generally relates to fusion proteins of immunoglobulins and interleukin-2 (IL-2). In addition, the present invention relates to polynucleotides encoding such fusion proteins, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the fusion proteins of the invention, and to methods of using them in the treatment of disease.

机译：本发明一般涉及免疫球蛋白和白介素2（IL-2）的融合蛋白。另外，本发明涉及编码此类融合蛋白的多核苷酸，以及包含此类多核苷酸的载体和宿主细胞。本发明进一步涉及产生本发明的融合蛋白的方法，以及使用它们治疗疾病的方法。

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公开/公告号BR112015002765A2

专利类型
公开/公告日2018-03-13

原文格式PDF
申请/专利权人 ROCHE GLYCART AG;
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申请/专利号BR20151102765
发明设计人 CHRISTIAN KLEIN;EKKEHARD MOESSNER;LAURENCE BERNARD PETERSON;LINDA WICKER;PABLO UMANA;RALF HOSSE;
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申请日2013-08-07
分类号A61K38/20;A61K47;A61K51/10;C07K14/55;C12N15/62;
国家 BR
入库时间 2022-08-21 12:54:01

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