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Innovative vaccine against the pandemic influenza a / h1n1 virus
Innovative vaccine against the pandemic influenza a / h1n1 virus
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机译:抗大流行性流感A / h1n1病毒的创新疫苗
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摘要
The invention relates to influenza virus vaccines, and in particular to an influenza virus which has at least its hemagglutinin gene comprising a D222 mutation, and a oseltamivir resistant neuraminidase gene. In some embodiments the influenza virus vaccine further comprises a matrix protein comprising a mutation that increases specific immune response in humans. The virus is useful for production of vaccines against hypervirulent and oseltamivir-resistant influenza.
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