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Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer
Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer
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机译:用于治疗或预防炎症性肠病,家族性腺瘤性息肉病和结肠癌的组合物和方法
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摘要
The present invention provides methods for preventing colon cancer by administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to prevent colon cancer, which composition inhibits COX-2. The present invention also provides methods for treating inflammation locally in the intestines comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat inflammation. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in alternative embodiments provides methods for treating pain locally in the intestines and treating inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, as well as for treating familial adenomatous polyposis (FAP).
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