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METHOD FOR PREDICTING TREATMENT EFFICACY OF PEGINTERFERON PLUS RIBAVIRIN TREATMENT IN A SUBJECT SUFFERING FROM HEPATITIS C
METHOD FOR PREDICTING TREATMENT EFFICACY OF PEGINTERFERON PLUS RIBAVIRIN TREATMENT IN A SUBJECT SUFFERING FROM HEPATITIS C
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机译：预测丙型肝炎病毒感染受试者中PEG干扰素加利巴韦林治疗效果的方法
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摘要
The present invention provides a method for predicting treatment efficacy of peginterferon plus ribavirin treatment in a subject suffering from chronic hepatitis C comprising: (a) measuring gene expression levels of genes comprising RSAD2, LOC26010, HERC5, HERC6, IFI44, SERPING1, IFITM3 and DDX60 of a blood sample from the subject after one week of the peginterferon plus ribavirin treatment; and (b) calculating a gene score according to cumulative fold change of the gene expression levels, when the gene score is equal to or higher than a cut-off value, the method predicts successful treatment of chronic hepatitis C with the peginterferon plus ribavirin treatment for the subject.
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