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COMPOSITIONS AND METHOD FOR REGULATING ADIPOSE TISSUE LIPOLYSIS, INSULIN-RESISTANCE, AND HYPERGLYCEMIA

机译:调节脂肪组织脂肪分解,胰岛素抵抗和高糖血症的组合物和方法

摘要

The present application discloses compositions and methods useful for controlling blood glucose and insulin resistance during the acute stress response. It is shown that Atglistatin can attenuate glucose excursions and insulin resistance arising from surgical procedures. It is further disclosed herein that Atglistatin is useful for inhibiting and preventing hyperglycemia and insulin resistance in many acute stress conditions, including, but not limited to, surgery, trauma/hemorrhage, burns, sepsis, myocardial infarction, and stroke.
机译:本申请公开了用于在急性应激反应期间控制血糖和胰岛素抵抗的组合物和方法。结果表明,Atglistatin可以减轻外科手术引起的葡萄糖偏移和胰岛素抵抗。本文进一步公开了在许多急性应激条件下,包括但不限于手术,创伤/出血,烧伤,败血症,心肌梗塞和中风,Atglistatin可用于抑制和预防高血糖症和胰岛素抵抗。

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