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Methods and Compositions for Activation of Innate Immune Responses Through RIG-I Like Receptor Signaling

机译:通过RIG-I样受体信号激活先天免疫反应的方法和成分

摘要

Compositions and methods are provided that enable activation of innate immune responses through RIG-I like receptor signaling. The compositions and methods incorporate synthetic nucleic acid pathogen associated molecular patterns (PAMPs) that comprise elements initially characterized in, and derived from, the hepatitis C virus genome.
机译:提供了使能够通过RIG-1样受体信号传导激活先天免疫应答的组合物和方法。所述组合物和方法结合了合成的核酸病原体相关的分子模式(PAMP),所述分子模式包括最初以丙型肝炎病毒基因组为特征并源自丙型肝炎病毒基因组的元件。

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