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Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction
Convergent approach to the total synthesis of telmisartan via a suzuki cross-coupling reaction
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机译:通过铃木交叉偶联反应聚合替米沙坦的全合成方法
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摘要
Methods of synthesizing the angiotensin II receptor antagonist telmisartan in high yield and purity are provided. The methods involve the coupling of two structurally distinct benzimidazole units via a Suzuki cross-coupling reaction. Methods of regioselectively synthesizing one of the benzimidazole units are also provided.
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