首页> 外国专利> Mesenchymal stem cell-hydrogel-biodegradable or mesenchymal stem cell-hydrogel-non-degradable support composition for alleviating or improving bullous epidermis

Mesenchymal stem cell-hydrogel-biodegradable or mesenchymal stem cell-hydrogel-non-degradable support composition for alleviating or improving bullous epidermis

机译:用于减轻或改善大疱表皮的间充质干细胞-水凝胶-可生物降解或间充质干细胞-水凝胶-不可降解的支持组合物

摘要

The present invention relates to a composition, a sheet and a method for producing the same comprising a mesenchymal stem cell-hydrogel-biodegradable support or a mesenchymal stem cell-hydrogel-non-degradable support. The sheet containing the mesenchymal stem cell-hydrogel biodegradable or non-degradable support according to the invention is a highly active stem cell as it is without the isolation process using a proteolytic enzyme. It can be applied to the affected area, and in the culture stage, the presence of extracellular substances such as collagen, laminin, pibronectin, and elastin secreted from mesenchymal stem cells is completely attached to the hydrogel, Compared with conventional dressings used for sexual epidermis, the skin regeneration and re-epithelialization ability are remarkably superior and exhibit an advantageous effect. [Selection] Figure 3
机译:本发明涉及一种包含间充质干细胞-水凝胶-不可生物降解的载体或间充质干细胞-水凝胶-不可生物降解的载体的组合物,片材及其制备方法。含有根据本发明的可生物降解或不可降解的间充质干细胞-水凝胶支持物的片材是高活性干细胞,因为它本身没有使用蛋白水解酶的分离过程。它可以应用于患处,在培养阶段,与间充质干细胞分泌的细胞外物质(如胶原蛋白,层粘连蛋白,皮布连蛋白和弹性蛋白)完全附着在水凝胶上,与用于性表皮的传统敷料相比,皮肤再生和再上皮能力明显优越,并显示出有利的作用。 [选择]图3

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