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METHOD FOR SCREENING CANDIDATE COMPOUND PRESENTING ANALGESIC EFFECT BY SPECIFICALLY COMBINING WITH FILM IN PERIPHERAL NERVE OR SPINAL CORD
METHOD FOR SCREENING CANDIDATE COMPOUND PRESENTING ANALGESIC EFFECT BY SPECIFICALLY COMBINING WITH FILM IN PERIPHERAL NERVE OR SPINAL CORD
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机译：通过与膜在周围神经或脊髓中的特定结合来筛选候选化合物的止痛效果的方法
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摘要
PROBLEM TO BE SOLVED: To provide a method for screening using as an index a compound which specifically combines with a film in a peripheral nerve or in a spinal cord.;SOLUTION: The method for screening a candidate compound with an analgesic effect includes the steps of: mixing a cyclic amine derivative shown by Chemical Formula (I) and a membrane fraction obtained by preparing from peripheral nerve or a spinal cord and obtaining a comparison sample; obtaining an evaluation sample in which the cyclic amine derivative and the membrane fraction are mixed with an evaluation compound; and comparing the physical property value of the comparison sample and that of the evaluation sample.;SELECTED DRAWING: Figure 4;COPYRIGHT: (C)2019,JPO&INPIT
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