首页> 外国专利> DETECTION METHOD AND KIT FOR PHOSPHOLIPID HYDROPEROXIDE-DEPENDENT CELL DEATH, PHOSPHOLIPID HYDROPEROXIDE-DEPENDENT CELL DEATH INHIBITOR, AND PREVENTIVE OR THERAPEUTIC AGENT FOR DISEASES ASSOCIATED WITH PHOSPHOLIPID HYDROPEROXIDE-DEPENDENT CELL DEATH

DETECTION METHOD AND KIT FOR PHOSPHOLIPID HYDROPEROXIDE-DEPENDENT CELL DEATH, PHOSPHOLIPID HYDROPEROXIDE-DEPENDENT CELL DEATH INHIBITOR, AND PREVENTIVE OR THERAPEUTIC AGENT FOR DISEASES ASSOCIATED WITH PHOSPHOLIPID HYDROPEROXIDE-DEPENDENT CELL DEATH

机译：磷脂酰过氧化物依赖的细胞死亡的检测方法和试剂盒，磷脂酰过氧化物依赖的细胞死亡抑制剂以及与磷脂酰过氧化物相关的疾病的预防或治疗剂

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摘要

PROBLEM TO BE SOLVED: To provide a detection method and kit for phospholipid hydroperoxide-dependent cell death, a phospholipid hydroperoxide-dependent cell death inhibitor, and a preventive or therapeutic agent for diseases by clarifying a factor involved in a cell death pathway caused by PHGPx depletion.SOLUTION: The invention provides a detection method for phospholipid hydroperoxide-dependent cell death having a step of detecting the production of phospholipid hydroperoxide and the activation of MEK in a cell sample.SELECTED DRAWING: Figure 27

机译：解决的问题：通过弄清PHGPx引起的细胞死亡途径的相关因素，提供一种检测方法和试剂盒，用于检测磷脂氢过氧化物依赖性细胞死亡，磷脂氢过氧化物依赖性细胞死亡抑制剂以及疾病的预防或治疗剂。消耗：解决方案：本发明提供了一种用于检测磷脂氢过氧化物依赖性细胞死亡的检测方法，该方法具有检测细胞样品中磷脂氢过氧化物的产生和MEK活化的步骤。图27

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公开/公告号JP2018126143A

专利类型
公开/公告日2018-08-16

原文格式PDF
申请/专利权人 KITASATO INSTITUTE;
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申请/专利号JP20180042367
发明设计人 IMAI HIROTAKA;
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申请日2018-03-08
分类号C12Q1/02;G01N33/53;G01N33/92;C12Q1/48;C12N15/113;C12Q1/6851;C12Q1/6876;C07K16/40;A61K45/00;A61K48/00;A61K31/713;A61P9/04;A61P43/00;C12Q1/6813;
国家 JP
入库时间 2022-08-21 13:14:10

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