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METHOD FOR EVALUATING EFFICACY OF CHEMORADIOTHERAPY IN SQUAMOUS-CELL CARCINOMA

机译:鳞状细胞癌化学疗法疗效评估方法

摘要

A method for evaluating an efficacy of a chemoradiotherapy against squamous cell carcinoma comprises the following steps (a) to (c): (a) detecting an expression level of at least one gene selected from a SIM2 gene and genes co-expressed with the SIM2 gene in a squamous cell carcinoma specimen isolated from a subject; (b) comparing the expression level detected in the step (a) with a reference expression level of the corresponding gene; and (c) determining that an efficacy of a chemoradiotherapy against squamous cell carcinoma in the subject is high if the expression level in the subject is higher than the reference expression level as a result of the comparison in the step (b).
机译:一种评估放化疗对鳞状细胞癌疗效的方法,包括以下步骤(a)至(c):(a)在从受试者分离的鳞状细胞癌标本中检测至少一种选自SIM2基因和与该SIM2基因共表达的基因的表达水平;(b)将步骤(a)中检测到的表达水平与相应基因的参考表达水平进行比较;和(c)作为步骤(b)中的比较的结果,如果受试者中的表达水平高于参考表达水平,则确定针对受试者的鳞状细胞癌的放化疗疗法的功效高。

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