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EXTRACELLULAR VESICLE MARKERS FOR STABLE ANGINA AND UNSTABLE ANGINA

机译:稳定型心绞痛和不稳定型心绞痛的细胞外囊泡标记

摘要

The present invention relates to the determination of protein markers associated with extracellular vesicles present in sub-fractions of plasma samples taken from people that experience chest pain and are suspected to experience ischemic heart disease. The invention relates to the use of the markers in the identification of subjects suffering from, or at risk of suffering from, an ischemic heart disease, in particular stable angina and unstable angina. Especially preferred markers are SerpinC1, SerpinG1, CD14, Cystatin C and SerpinF2.
机译:本发明涉及测定与血浆样品亚部分中存在的细胞外囊泡有关的蛋白质标志物,所述血浆样品是从患有胸痛并被怀疑患有缺血性心脏病的人身上提取的。本发明涉及标记物在鉴定患有缺血性心脏病,或患有缺血性心脏病,特别是稳定型心绞痛和不稳定型心绞痛的受试者中的用途。特别优选的标记是SerpinC1,SerpinG1,CD14,胱抑素C和SerpinF2。

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