首页> 外国专利> 3-PHENYL-THIAZOLO3,2-ABENZIMIDAZOLE DERIVATIVES AS ALDEHYDE DEHYDROGENASE 1 (ALDH-1) MODULATORS FOR THE TREATMENT OF BREAST CANCER OR LEUKEMIA, AND FOR MANIPULATING CULTURED ALDH-1 POSITIVE BREAST CANCER OR LEUKEMIA CELLS

3-PHENYL-THIAZOLO3,2-ABENZIMIDAZOLE DERIVATIVES AS ALDEHYDE DEHYDROGENASE 1 (ALDH-1) MODULATORS FOR THE TREATMENT OF BREAST CANCER OR LEUKEMIA, AND FOR MANIPULATING CULTURED ALDH-1 POSITIVE BREAST CANCER OR LEUKEMIA CELLS

机译：3-苯基噻唑并[3,2-A]苯并咪唑衍生物作为醛脱氢酶1（ALDH-1）调节剂，用于治疗乳腺癌或白血病，以及操纵培养的ALDH-1阳性乳腺癌或白血病。

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摘要

The present invention relates to benzo-thiazolo-imidazole compounds and their uses. Moreover, the present invention relates to pharmaceutical compositions comprising such a benzo-thiazolo-imidazole compound. Furthermore, the present invention relates to the use of such a benzo-thiazolo-imidazole compound for the manipulation of cultured cells.

机译：本发明涉及苯并噻唑并咪唑化合物及其用途。而且，本发明涉及包含这种苯并噻唑并咪唑化合物的药物组合物。此外，本发明涉及这种苯并噻唑并咪唑化合物在处理培养细胞中的用途。

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公开/公告号EP3070092B1

专利类型
公开/公告日2018-11-07

原文格式PDF
申请/专利权人 KING SAUD UNIVERSITY;KING FAISAL SPECIALIST HOSPITAL & RESEARCH CENTRE;
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申请/专利号EP20150159402
发明设计人 AL DHFYAN ABDULLAH OMAR;ABDEL-AZIZ HATEM ABDEL-KADER;MANOGRAN PULICAT SUBRAMANIAN;AL-ALWAN MONTHER MOHAMMAD;GHEBEH HAZEM M. BACHIR;EL-TAHIR KAMAL EL-DIN HUSSEIN;
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申请日2015-03-17
分类号C07D513/04;A61K31/4188;A61P35;
国家 EP
入库时间 2022-08-21 13:19:33

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