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首页> 外国专利> METHOD FOR PREPARATION OF ULTRATHIN DONOR CORNEAL TRANSPLANTS FOR POSTERIOR LAYERED KEROPLASTY BY SEQUENTIAL APPLICATION OF AUTOMATIC MICROKERATOME AND EXCIMER LASER

METHOD FOR PREPARATION OF ULTRATHIN DONOR CORNEAL TRANSPLANTS FOR POSTERIOR LAYERED KEROPLASTY BY SEQUENTIAL APPLICATION OF AUTOMATIC MICROKERATOME AND EXCIMER LASER

机译：自动微角膜刀和准分子激光的连续应用制备超薄型角膜移植角膜移植的方法

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FIELD: medicine.;SUBSTANCE: invention is designed to form an ultrathin corneal disc (transplant) for posterior layered keratoplasty. At the first stage, the donor cornea, preserved in the Borzenka-Moroz medium, is mounted on an artificial front chamber. Ultrasound or OCT pachymetry (usually the thickness in the center of 750-900 microns) is performed. The first section is made with the Moria SLK 2 microkeratome with a longitudinal-type turbine with a caliper head of 450-500-550 mcm. Then ultrasound or OCT pachymetry is repeated. At the second stage, ablation with a flat beam using an excimer laser ophthalmic unit Microscan Visum (Optosystems, Troitsk) is performed to the depth necessary to obtain an ultrathin transplant (the residual thickness in the center of the transplant is 120-140 mcm). The excimer laser wavelength is 193 nm, repetition rate is 500 Hz, laser spot diameter is 0.9 mm, maximum ablation diameter is 9.0 mm, the ablation depth, as a rule, does not exceed 100 mcm (30-100 mcm). A piercer of the desired diameter (8-8.5 mm) is used to cut out the desired transplanto for ALK from the resulting blank. The obtained transplant thickness in the hydrated form in the central zone does not exceed 140 microns. After transplant dehydration in the eye of the recipient (usually not less than 30%), its thickness, respectively, does not exceed 100 microns.;EFFECT: predictable manufacture of a transplant with a given thickness without risk of perforation of the donor cornea and its rejection.;2 ex
机译：技术领域：本发明旨在形成用于后分层角膜移植术的超薄角膜盘（移植物）。在第一阶段，将保存在Borzenka-Moroz培养基中的供体角膜安装在人造前腔上。进行超声或OCT测厚法（通常在750-900微米中心的厚度）。第一部分由Moria SLK 2微型角膜刀制成，该角膜刀带有纵向型涡轮，其卡钳头为450-500-550 mcm。然后重复超声或OCT测厚法。在第二阶段，使用准分子激光眼科仪器Microscan Visum（Optosystems，Troitsk）用平光束烧蚀至获得超薄移植物所需的深度（移植物中心的残留厚度为120-140 mcm）。 。准分子激光波长为193 nm，重复频率为500 Hz，激光光斑直径为0.9 mm，最大烧蚀直径为9.0 mm，烧蚀深度通常不超过100 mcm（30-100 mcm）。使用所需直径的穿孔器（8-8.5毫米）从所得的坯料中切出所需的ALK移植物。在中心区域以水合形式获得的移植物厚度不超过140微米。移植后在接受者眼中脱水（通常不小于30％）后，其厚度分别不超过100微米。效果：可预测地制造具有给定厚度的移植物，而无供体角膜和角膜穿孔的风险它的拒绝。; 2 ex

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