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METHOD FOR TREATMENT OF LOCALLY ADVANCED BREAST CANCER WITH TUMOUR SKIN ULCERATION

机译:肿瘤皮肤溃疡治疗局部晚期乳腺癌的方法

摘要

FIELD: medicine.;SUBSTANCE: to treat locally advanced breast cancer with tumour skin ulceration, radiation therapy is performed in the mode of medium dose fractionation on the area of the mammary gland base and regional lymph drainage zone. In addition, prior to irradiation, a "Coletex-5-ftor" hydrogel tissue is applied to the tumour region for 5-7 days, 2-3 times daily. Prior to irradiation, a "Coletex-5-ftor" hydrogel tissue is applied to the area of skin tumour ulcers, where nitric acid silver is added as 0.2-2.0 wt %. At that, the marginal zones of skin tumour ulceration are treated with a hydrogel material on the basis of "Coletex-gel-DNA" sodium alginate, where betulin-containing birch bark extract is added as 0.1-1.5 wt %. After application of these hydrogels, a thermo-net is placed on top of them on the breast area, the net is cut out to overlap the ulcer area by 1.0-1.5 cm. Prior to radiotherapy, field markings in the ulcer area is carried out on the thermo-net.;EFFECT: method ensures accelerated tumour ulcers healing, reduced drug load, reduced toxicity and a possibility of carrying out radiation therapy without interruption, reduced traumatization of tissues in the irradiation zone, and cessation of inflammatory processes.;2 ex
机译:领域:医学;研究对象:为治疗具有肿瘤皮肤溃疡的局部晚期乳腺癌,放射治疗以中等剂量分级的方式在乳腺基部和区域淋巴引流区进行。另外,在辐射之前,将“ Coletex-5-ftor”水凝胶组织施用于肿瘤区域5-7天,每天2-3次。在辐照之前,将“ Coletex-5-ftor”水凝胶组织施加到皮肤肿瘤溃疡的区域,其中以0.2-2.0wt%的浓度添加硝酸银。此时,基于“ Coletex-gel-DNA”藻酸钠,用水凝胶材料处理皮肤肿瘤溃疡的边缘区域,其中以0.1-1.5wt%的量添加含桦木素的桦树皮提取物。涂上这些水凝胶后,将热网放在乳房上方的热网上方,将网切开以覆盖溃疡区域1.0-1.5厘米。在放疗之前,在热网上对溃疡区域进行现场标记。效果:该方法可确保加速肿瘤溃疡愈合,减少药物负荷,降低毒性,并可以进行放射治疗而不会中断,减少组织的创伤在辐照区,并停止炎症过程。; 2 ex

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