首页> 外国专利> METHOD FOR DIAGNOSIS OF MYOCARDIUM MORPHOFUNCTIONAL DISTURBANCES FOR CHILDREN OLDER THAN 5 YEARS WITH BRONCHOPULMONARY DISEASES ASSOCIATED WITH EXPOSURE TO BENZENE, TOLUENE, PHENOL AND FORMALDEHYDE

METHOD FOR DIAGNOSIS OF MYOCARDIUM MORPHOFUNCTIONAL DISTURBANCES FOR CHILDREN OLDER THAN 5 YEARS WITH BRONCHOPULMONARY DISEASES ASSOCIATED WITH EXPOSURE TO BENZENE, TOLUENE, PHENOL AND FORMALDEHYDE

机译:诊断五年以上合并苯,甲苯,苯酚和甲醛的支气管肺疾病的儿童的心肌形态功能障碍的诊断方法

摘要

FIELD: medicine.;SUBSTANCE: concentration benzene, toluene, phenol and formaldehyde is determined in the chold's blood sample. If it exceeds the background value, functional and laboratory parameters are determined. The following is determined as the functional parameters: myocardium electrophysiological function, heart rate variability, heart contractile function and intracardiac hemodynamics, valvular function. The following is determined as laboratory parameters: white blood cells level, level of antioxidant activity AOA, malondialdehyde MDA, high-sensitive C-reactive protein, and apolipoproteins. In case of sinus bradycardia/tachycardia, eutonic initial vegetative tonus, accompanied by predominating activity of the autonomic nervous system parasympathetic division, asympathicotonic/hypersympathicotonic reactivity, increase in systolic blood pressure in the pulmonary artery, transient right ventricular diastolic dysfunction, as well as in case of white blood cell excess by 20% and more, MDA - 1.3 times or more, high-sensitivity C-reactive protein - 1.8 times or more, reduction of AOA 1.2 times or more and at increased apolipoprotein A1 and decreased "apolipoprotein B/apolipoprotein A1" factor relative to the physiological age norm, morphofunctional myocardium disorders are diagnised for children older than 5 years with bronchopulmonary diseases associated with exposure to benzene, toluene, phenol and formaldehyde.;EFFECT: method provides reliable and informative diagnosis of morphofunctional myocardium disorders, timely treatment and prevention of complications development by assessing the most significant functional and laboratory parameters.;12 tbl, 1 ex
机译:领域:医药;物质:在车hold的血液样本中测定苯,甲苯,苯酚和甲醛的浓度。如果超过背景值,则确定功能和实验室参数。确定以下功能参数:心肌电生理功能,心率变异性,心脏收缩功能和心内血流动力学,瓣膜功能。确定以下参数作为实验室参数:白细胞水平,抗氧化活性水平AOA,丙二醛MDA,高敏感性C反应蛋白和载脂蛋白。在窦性心动过缓/心动过速的情况下,自律性初生植物性张力,伴有自主神经系统副交感神经分裂的主要活动,无交感神经/高交感神经性反应性,肺动脉收缩压升高,短暂性右心室舒张功能障碍以及白细胞过量超过20%的情况,MDA-1.3倍或更多,高敏C反应蛋白-1.8倍或更多,AOA降低1.2倍或更多,载脂蛋白A1增加而“载脂蛋白B /载脂蛋白A1“因子相对于生理年龄正常,对于5岁以上患有与苯,甲苯,苯酚和甲醛有关的支气管肺疾病的儿童,应诊断为形态功能性心肌病。 ,及时治疗和预防并发症的发生评估最重要的功能和实验室参数。; 12 tbl,1前

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