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首页> 外国专利> VACCINE INFLUENZA VIRUS STRAIN A/17/Bolivia/2013/6585 (H1N1)pdm09 FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN

VACCINE INFLUENZA VIRUS STRAIN A/17/Bolivia/2013/6585 (H1N1)pdm09 FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN

机译：疫苗流感病毒株A / 17 /玻利维亚/ 2013/6585（H1N1）pdm09，用于制备成人和儿童的实时流感鼻内疫苗

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FIELD: medicine.;SUBSTANCE: invention refers to medical virology and concerns influenza virus strain. Characterized vaccine strain A/17/Bolivia/2013/6585 (H1N1)pdm09 - reassortant, produced by crossing "wild" virus A/Bolivia/559/2013 (H1N1)pdm09 with cold-adapted heat-sensitive virus A/Leningrad/134/17/57 (H2N2) - donor of attenuation, safe for humans. Strain A/17/Bolivia/2013/6585 (H1N1)pdm09 actively propagated in developing chicken embryos at optimal temperature of 32 °C, characterised by thermal sensitivity and cold adaptation and safety for laboratory animals. Reassortant deposited in State collection of viruses of FGBU "FNICEM nam. N.F. Gamalei" of the Ministry of health of Russia Research Institute of virology. D. I. Ivanovskogo under №2809.;EFFECT: invention can be used in practical health services for preventing influenza incidence in adults and children.;1 cl, 5 tbl
机译：技术领域本发明涉及医学病毒学，涉及流感病毒株。表征的疫苗株A / 17 /玻利维亚/ 2013/6585（H1N1）pdm09-重配体，是通过将“野生”病毒A /玻利维亚/ 559/2013（H1N1）pdm09与冷适应的热敏感病毒A / Leningrad / 134杂交产生的/ 17/57（H2N2）-衰减的捐赠者，对人类安全。菌株A / 17 / Bolivia / 2013/6585（H1N1）pdm09在32℃的最佳温度下在发育中的鸡胚中积极繁殖，其特点是具有热敏感性，冷适应性和对实验动物的安全性。重配物存放在俄罗斯病毒研究所卫生部FGBU“ FNICEM nam。N.F. Gamalei”病毒的国家收集物中。 D. I. Ivanovskogo，№2809。;效果：本发明可用于预防成年人和儿童流感的实用卫生服务。1cl，5 tbl

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