首页> 外国专利> STRAIN A №2155/BAIKAL/2013 OF MURRAIN VIRUS APHTAE EPIZOOTICAE TYPE A FOR CONTROL OF ANTIGENIC AND IMMUNOGENIC ACTIVITY AND TO PRODUCE BIOPREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PREVENTION OF MURRAIN TYPE A

STRAIN A №2155/BAIKAL/2013 OF MURRAIN VIRUS APHTAE EPIZOOTICAE TYPE A FOR CONTROL OF ANTIGENIC AND IMMUNOGENIC ACTIVITY AND TO PRODUCE BIOPREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PREVENTION OF MURRAIN TYPE A

机译：品系A 21.6 / BAIKAL / 2013鼠型鼠疫埃博佐病毒，用于控制抗原和免疫活性，并为生物诊断和专门预防鼠型A

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FIELD: veterinary science.;SUBSTANCE: invention relates to veterinary virology and biotechnology and concerns new murrain virus strain Aphtae epizooticae type A family of Picornaviridae, genus Aphtovirus, deposited in collection of FGBU “VNIIZZH” under registration number murrain strain A No. 2155/Baikal/2013 (industrial). Presented strain is reproduced in monolayer swine kidney cell culture (SC), continuous kidney cell cultures of siberian mountain goat (PSGK-30), VNK-21 and IB-RS-2 during 18÷24 hours of incubation of virus yield in said cell cultures reaches levels of 6.33÷7.5 lg TCD₅₀/cm³. Multiplicity of infection (1÷10 TCD/cell) causes CPP after 5 hours, maintaining initial characteristics, when passaging in cell cultures throughout 5 passages.;EFFECT: presented strain may be used for control of antigenic and immunogenic activity and to produce biopreparations for diagnosis and specific prevention of murrain type A.;1 cl, 6 tbl, 7 ex

机译：发明领域本发明涉及兽医病毒学和生物技术，并涉及新的鼠疫病毒菌株Aphtae epizooticae Aphtovirus属的角膜杆状病毒科的家族，以登记号murrain菌株A No. 2155 /保藏在FGBU“ VNIIZZH”的集合中。贝加尔湖/ 2013年（工业）。在所述细胞中病毒产量温育的18÷24小时内，在单层猪肾细胞培养物（SC），西伯利亚山山羊的连续肾细胞培养物（PSGK-30），VNK-21和IB-RS-2中复制了提出的菌株。培养物达到6.33÷7.5 lg TCD _{50 / cm ^{3 的水平。感染的多重性（1÷10 TCD /细胞）在5小时后传给CPP，在传代培养5代的细胞培养物中传代时保持初始特性。效果：所展示的菌株可用于控制抗原和免疫原性并生产生物制剂。诊断和特异性预防A型偏头痛; 1 cl，6 tbl，7 ex}}

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公开/公告号RU2603255C9

专利类型
公开/公告日2017-03-07

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE FEDERALNYJ TSENTR OKHRANY ZDOROVYA ZHIVOTNYKH (FGBU VNIIZZH);
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申请/专利号RU20150115872
发明设计人 LOZOVOJ DMITRIJ ANATOLEVICH (RU);MISHCHENKO ALEKSEJ VLADIMIROVICH (RU);KREMENCHUGSKAYA SVETLANA REVDITOVNA (RU);SHCHERBAKOV ALEKSEJ VLADIMIROVICH (RU);MIKHALISHIN DMITRIJ VALEREVICH (RU);MAJOROVA TAMARA KONSTANTINOVNA (RU);LUGOVSKAYA NATALIYA NIKOLAEVNA (RU);RUMYANTSEVA OLGA SERGEEVNA (RU);DIEV VYACHESLAV IVANOVICH (RU);
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申请日2015-04-28
分类号A61K39/135;C12N7;
国家 RU
入库时间 2022-08-21 13:23:49

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