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NMDA NMDA Compound for detecting zinc ion at NMDA receptor and a fluorescence sensor containing the same for detecting zinc ion at NMDA receptor

机译:NMDA NMDA用于检测NMDA受体处锌离子的化合物和包含该化合物的荧光传感器,用于检测NMDA受体处的锌离子

摘要

The present invention relates to a compound for detecting zinc ions in an NMDA receptor, and a fluorescence probe containing the same for detecting zinc ions in an NMDA receptor. The compound for detecting zinc ions in an NMDA receptor can detect zinc ions through a two-photon fluorescence change showed by collecting zinc ions around an NMDA receptor after being coupled with the NMDA receptor. Accordingly, by sensing a change of zinc ions according to neural stimulation, the compound can be used in neuropathology research and can be usefully contained as a composition for diagnosing or detecting neuropathic diseases comprising the compound as an effective component.
机译:本发明涉及一种用于检测NMDA受体中的锌离子的化合物,以及一种包含用于检测NMDA受体中的锌离子的荧光探针。用于检测NMDA受体中锌离子的化合物可以通过与NMDA受体偶联后在NMDA受体周围收集锌离子而显示的双光子荧光变化来检测锌离子。因此,通过根据神经刺激感测锌离子的变化,该化合物可以用于神经病理学研究,并且可以有效地包含在诊断或检测中,该化合物包含该化合物作为有效成分的组合物。

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