首页> 外国专利> bli-3 C. elegans C. ELEGANS WITH BLI-3 ACTIVITY KNOCKED DOWN FOR SCREENING OXIDATIVE STRESS INDUCING MATERIAL AND OXIDATIVE STRESS INDUCING MATERIAL SCREENING METHOD USING THE SAME

bli-3 C. elegans C. ELEGANS WITH BLI-3 ACTIVITY KNOCKED DOWN FOR SCREENING OXIDATIVE STRESS INDUCING MATERIAL AND OXIDATIVE STRESS INDUCING MATERIAL SCREENING METHOD USING THE SAME

机译：具有bli-3活性的bli-3秀丽隐杆线虫，用于筛选氧化应激诱导材料和使用相同方法筛选氧化应激诱导材料

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摘要

The present invention relates to a method for screening for oxidative stressors,C. elegansAnd a method for screening oxidative stress inducers using the same. The bli-3 gene knockdown (bli-3 gene)C. elegansAnd bli-3 gene function is normalC.ElegansWere exposed to the test substance, and the fluorescent intensity and bli-3 gene function attributable to the active oxygen species of C. elegans with reduced bli-3 gene function were normalC.ElegansTo determine whether the test substance is an indirect oxidative stressor or a direct oxidative stressor, or to determine whether the bli-3 gene function is decreasedC.ElegansAnd bli-3 gene function is normalC.ElegansTo determine whether the test substance is an indirect oxidative stressor or a direct oxidative stressor.;

机译：本发明涉及一种筛选氧化应激源I C的方法。线虫以及使用该方法筛选氧化应激诱导剂的方法。 bli-3基因敲低（bli-3基因）C。线虫和bli-3基因功能正常 C。 Elegans 暴露于测试物质，荧光强度和bli-3基因功能可归因于bli-3基因功能降低的秀丽线虫的活性氧是正常的 C。 Elegans 为确定测试物质是间接氧化应激源还是直接氧化应激源，或确定bli-3基因功能是否降低 C。 Elegans 和bli-3基因功能是否正常 C。 Elegans 确定测试物质是间接氧化应激源还是直接氧化应激源。 展开▼

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公开/公告号KR101764832B1

专利类型

公开/公告日2017-08-03

原文格式PDF

申请/专利权人 서울시립대학교 산학협력단;
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申请/专利号KR20150059194

发明设计人 안정민;니베디타 챠터지;양지수;최진희;
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申请日2015-04-27

分类号A01K67/027;G01N33/50;

国家 KR

入库时间 2022-08-21 13:25:01

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