首页> 外国专利> GLYCOSIDE COMPOUND METHOD FOR PRODUCING THIOETHER ETHER METHOD FOR PRODUCING ETHER METHOD FOR PRODUCING GLYCOSIDE COMPOUND METHOD FOR PRODUCING NUCLEIC ACID

GLYCOSIDE COMPOUND METHOD FOR PRODUCING THIOETHER ETHER METHOD FOR PRODUCING ETHER METHOD FOR PRODUCING GLYCOSIDE COMPOUND METHOD FOR PRODUCING NUCLEIC ACID

机译:乙醇胺的合成方法乙醇的合成方法乙醇的合成方法乙醇酸的合成方法

摘要

There is provided a glycoside compound capable of providing phosphoramidite, and the phosphoramidite can be produced at a low cost and the nucleic acid can be prepared with high yield and high purity. A glycoside compound represented by the following formula (1). In the formula (1) B is a nucleic acid base skeleton, optionally an atomic group having a protecting group, R 1 and R 2 are each a hydrogen atom or a protecting group, or R 1 and R 2 are taken together to form an atomic group optionally represented by the following formula (R 1 R 2 A) or (R 1 R 2 B) Each R 1a is a hydrogen atom, a linear or branched alkyl group or the like, L 1 is an unsubstituted or alkyl-substituted ethylene group, R 3 is a group represented by the following formula (R 3 ) In the formula (R 3 ), n is a positive integer, [D 1 ] is an electron withdrawing unit.
机译:提供了一种能够提供亚磷酰胺的糖苷化合物,该亚磷酰胺可以低成本生产,并且可以高收率和高纯度制备核酸。下式(1)表示的糖苷化合物。式(1)中,B是核酸碱基骨架,可以是具有保护基的原子团,R 1 和R 2 分别是氢原子或保护基。基,或R 1 和R 2 一起形成一个原子团,可选地由下式表示:(R 1 R 2 A)或(R 1 R 2 B)每个R 1a 是氢原子,直链或支链烷基L 1 为未取代或烷基取代的亚乙基,R 3 为下式(R 3 )在式(R Sup> 3 1 ]为吸电子单元。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号