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N--1H--3- MELK Novel N-aryl-1H-pyrazolopyridin-3-amine derivatives or pharmaceutically acceptable salts thereof preparation method therof and pharmaceutical composition for use in preventing or treating MELKmaternal embryonic leucine zipper kinase activity related diseases containing the same as an active ingredient
N--1H--3- MELK Novel N-aryl-1H-pyrazolopyridin-3-amine derivatives or pharmaceutically acceptable salts thereof preparation method therof and pharmaceutical composition for use in preventing or treating MELKmaternal embryonic leucine zipper kinase activity related diseases containing the same as an active ingredient
The present invention relates to an N-aryl-1H-pyrazolopyridin-3-amine derivative or a pharmaceutically acceptable salt thereof, a process for the preparation thereof, and a method for the prevention or treatment of MELK (maternal embryonic leucine zipper kinase) /RTI The N-aryl-1H-pyrazolopyridine-3-amine derivative according to the present invention is excellent in the effect of inhibiting the expression of MELK, and thus can be used as an agent for treating cancer such as breast cancer, lung cancer, bladder cancer, lymphoma, polymorphonalephritis, cervical cancer, And can be usefully used for preventing or treating related diseases.
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