首页> 外国专利> diesel exhaust particle Biomarker for identification of genes related to inflammatory response after exposure to diesel exhaust particle and the method of identification using thesame

diesel exhaust particle Biomarker for identification of genes related to inflammatory response after exposure to diesel exhaust particle and the method of identification using thesame

机译:柴油机排气颗粒物生物标志物,用于鉴定与柴油机排气颗粒物接触后炎症反应相关的基因,以及使用相同方法进行鉴定的方法

摘要

The present invention relates to an inflammatory reaction-related biomarker for confirming the exposure of diesel exhaust particles, which is one of the fine particles exposed in the environment, and a method of using the same. Specifically, The present invention relates to a biomarker for detecting an inflammatory reaction-related biomarker, which is increased or decreased, and a method for identifying specific exposure to diesel exhaust fine particles using the same. The biomarker of the present invention comprises a DNA microarray chip, Can be used to monitor and determine the contamination of diesel exhaust particulates in environmental samples and can be used as a tool to identify toxic action mechanisms specifically induced by diesel exhaust particulates.
机译:炎性反应相关生物标志物及其使用方法技术领域本发明涉及一种用于确认暴露于环境中的微粒之一的柴油机废气颗粒的暴露的炎性反应相关生物标志物及其使用方法。具体地,本发明涉及用于检测增加或减少的与炎症反应相关的生物标志物的生物标志物,以及使用该生物标志物确定对柴油机排气微粒的特异性暴露的方法。本发明的生物标记物包括DNA微阵列芯片,可用于监测和确定环境样品中柴油机尾气颗粒的污染,并且可用作鉴定由柴油机尾气颗粒特异性诱导的毒性作用机理的工具。

著录项

  • 公开/公告号KR101749566B1

    专利类型

  • 公开/公告日2017-06-22

    原文格式PDF

  • 申请/专利权人 한국과학기술연구원;

    申请/专利号KR20150117209

  • 发明设计人 류재천;송미경;조윤;정승찬;

    申请日2015-08-20

  • 分类号C12Q1/68;C40B40/06;

  • 国家 KR

  • 入库时间 2022-08-21 13:25:16

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