首页> 外国专利> TSC1 mTOR miRNA The pharmaceutical composition for the prophylaxis or treatment of epilepsy or seizure-related disease targeting miRNA to regulate the expression of TSC1 and mTOR protein and method for screening

TSC1 mTOR miRNA The pharmaceutical composition for the prophylaxis or treatment of epilepsy or seizure-related disease targeting miRNA to regulate the expression of TSC1 and mTOR protein and method for screening

机译：TSC1 mTOR miRNA用于预防或治疗靶向miRNA的癫痫或癫痫相关疾病的药物组合物，以调节TSC1和mTOR蛋白的表达以及筛选方法

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摘要

The present invention relates to a pharmaceutical composition and a screening method for preventing or treating epilepsy or seizure related diseases, and more particularly, to a method of screening for a compound of the present invention by using miRNA regulatory substances to increase the expression of TSC1 and reduce the expression of mTOR, And moreover, to provide a pharmaceutical composition for the fundamental treatment of an epileptic or seizure-related disease.;

机译：本发明涉及用于预防或治疗癫痫或癫痫相关疾病的药物组合物和筛选方法，更具体地，涉及通过使用miRNA调节物质增加TSC1和mRNA表达来筛选本发明化合物的方法。降低mTOR的表达，此外，提供用于癫痫或癫痫相关疾病的基本治疗的药物组合物。

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公开/公告号KR101738923B1

专利类型
公开/公告日2017-05-24

原文格式PDF
申请/专利权人 (주) 어드밴스드 엔티;
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申请/专利号KR20150154780
发明设计人 주건;이순태;이상건;문장섭;김만호;정근화;
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申请日2015-11-04
分类号A61K48/00;A61K31/713;A61K9/00;G01N33/50;
国家 KR
入库时间 2022-08-21 13:25:30

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