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Composition comprising exosomes extracted from stem cells which differentiate into chondrocytes for inducing chondrogenic differentiation or regenerating cartilage tissue
Composition comprising exosomes extracted from stem cells which differentiate into chondrocytes for inducing chondrogenic differentiation or regenerating cartilage tissue
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机译：包含从干细胞中提取的外泌体的组合物，所述外泌体可分化成软骨细胞以诱导软骨分化或软骨组织再生
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摘要
The present invention relates to a composition for inducing differentiation of chondrocytes or regenerating cartilage tissue comprising exosome extracted from stem cells differentiated into chondrocytes as an active ingredient, a medium composition for inducing differentiation of chondrocytes comprising the composition, And to pharmaceutical compositions for the treatment of injections and cartilage diseases. The composition for inducing chondrocyte differentiation or cartilage regeneration according to an embodiment of the present invention contains exosome extracted from stem cells differentiating into chondrocytes as an effective factor. The exosomes secreted during the differentiation of stem cells contain genes and proteins related to cell proliferation and regeneration of stem cells, as well as growth factors related to chondrocyte differentiation, and thus induce regeneration of injured cartilage tissue. In addition, the adverse effect on the existing cell treatment agent can be minimized, and the cell can be stably and rapidly delivered as a cell-derived carrier. Therefore, it is an injectable composition for prevention and treatment of cartilage diseases, which not only reduces the suffering of patients by simple procedures, but also enables continuous and effective treatment of cartilage disease after the treatment.
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