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USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNF-a THERAPY

机译:拉喹莫德治疗一线抗TNF-a失败的克罗恩病患者的治疗

摘要

#$%^&*AU2017200472A120170209.pdf#####Abstract This application provides for a method of treating a human patient afflicted with anti-TNFa refractory Crohn's disease, of treating a human patient afflicted with nonfibrostenotic Crohn's disease, and of treating a human patient whose Crohn's disease had not been surgically treated, the method comprising periodically administering to the patient an amount of laquinimod or pharmaceutically acceptable salt thereof effective to treat the patient. This application also provides for a method of inducing or maintaining clinical remission in a human patient afflicted with Crohn's disease comprising periodically administering to the patient an amount of laquinimod effective to induce or maintain clinical remission in the patient, which amount of laquinimod is less than 0.5 mg/day.
机译:#$%^&* AU2017200472A120170209.pdf #####抽象本申请提供了一种治疗人类的方法。抗TNFa难治性克罗恩病患者疾病,治疗患有非糖尿病的人类患者纤维性克罗恩病,以及治疗人类克罗恩病未经手术治疗的患者治疗后,该方法包括定期给药给患者一定量的拉喹莫德或药物有效治疗患者的可接受的盐。本申请还提供了一种诱导或诱导的方法。维持患病患者的临床缓解患有克罗恩氏病,包括定期服用给患者一定量的拉喹莫德,可有效诱导或维持患者的临床缓解,拉喹莫德的剂量少于0.5毫克/天。

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