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Methods for genetic study and analysis of populations
Methods for genetic study and analysis of populations
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机译:群体遗传研究和分析方法
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摘要
1. A method for building a database of profiles variety of labels (PDM) comprising the steps of: a) sequencing a plurality of markers rRNA of a sample, wherein said sample comprises a microbial population, and wherein each marker comprises a polymorphic rRNA gene sequence microbial rRNA and wherein the plurality of markers rRNA provides an accurate representation of the microbial population from said sample; b) determining the abundance in the sample, each of said plurality of markers rRNA; c) transducing the abundance of each marker rRNA in an electrical output signal; d) storing said electrical output signals produced in step c) in a matrix data structure and associating, in said structure, each output signal with the corresponding marker sequence rRNA whose abundance became an output signal; e) providing the abundances of one or more sample parameters that are associated with said sample; f) transducing the abundances of each parameter shows an electrical output signal; g) storing said electrical output signals produced in step f) in a matrix data structure associating in said structure and each output signal with parameter whose abundance sample became an output signal; h) designed as PDM signals electrical output produced in corresponding to the plurality of abundances markers rRNA and the electrical output signals produced in corresponding to the one or more abundances sample parameters step f) step c); i) repeating steps ah to a plurality of different samples, and design, as PDM data base, the plurality of PDM stored in said data structure.
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