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Compositions and methods for the treatment and prevention of antipsychotic medication-induced weight gain

机译:用于治疗和预防抗精神病药物引起的体重增加的组合物和方法

摘要

The invention provides methods and compositions for the treatment of a subject having a psychiatric disease or disorder based upon the subject's genotype and/or the number of risk alleles carried by the subject, which risk alleles have been found by the present inventors to predispose a subject to antipsychotic medication induced weight gain (AIWG). The methods of the invention also provide for different treatments, or different treatment regimens, for the subject depending on the subject's risk of AIWG. Related compositions, in the form of kits, systems, and computer-readable media are also provided.
机译:本发明提供了基于受试者的基因型和/或受试者携带的风险等位基因的数目来治疗患有精神疾病或病症的受试者的方法和组合物,本发明人已经发现这些风险等位基因使受试者容易患病抗精神病药物引起的体重增加(AIWG)。本发明的方法还根据受试者的AIWG风险为受试者提供不同的治疗或不同的治疗方案。还提供了试剂盒,系统和计算机可读介质形式的相关组合物。

著录项

  • 公开/公告号IL247410D0

    专利类型

  • 公开/公告日2016-11-30

    原文格式PDF

  • 申请/专利权人 CENTRE FOR ADDICTION AND MENTAL HEALTH;

    申请/专利号IL20160247410

  • 发明设计人

    申请日2016-08-22

  • 分类号A61K31/445;A61K31/519;C12Q1/6883;G01N33/50;G16B20;

  • 国家 IL

  • 入库时间 2022-08-21 13:38:56

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