首页> 外国专利> SUBSTITUTED PYRROLIDINES AS A FACTOR XIA INHIBITORS FOR TREATMENT OF TROMBOEMBOLIC DISEASES

SUBSTITUTED PYRROLIDINES AS A FACTOR XIA INHIBITORS FOR TREATMENT OF TROMBOEMBOLIC DISEASES

机译：取代的吡咯烷二酮类化合物作为治疗腰椎间盘疾病的Xia抑制剂

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摘要

The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the substituents are as defined in the description). The compounds of the general formula (I) are inhibitors of factor XIa, and are useful in the prevention of and/or therapy for thromboembolic diseases.

机译：本发明提供了通式（I）的化合物，其盐和N-氧化物，及其溶剂化物和前药（其中取代基如说明书中所定义）。通式（I）的化合物是因子XIa的抑制剂，可用于预防和/或治疗血栓栓塞性疾病。

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公开/公告号DK2855452T3

专利类型
公开/公告日2017-07-03

原文格式PDF
申请/专利权人 ONO PHARMACEUTICAL CO. LTD.;
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申请/专利号DK20130727822T
发明设计人 COURTNEY STEVE;YARNOLD CHRIS;ICHIHARA OSAMU;FLANAGAN STUART;IMAGAWA AKIRA;KONDO TAKASHI;NISHIYAMA TAIHEI;
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申请日2013-05-23
分类号C07D401/14;A61K31/4025;A61K31/41;A61K31/454;A61K31/496;A61K31/5377;A61P9;C07D401/04;C07D403/04;C07D403/14;C07D413/04;C07D413/14;
国家 DK
入库时间 2022-08-21 13:39:20

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