首页> 外国专利> pharmaceutical composition, and methods for reducing plaque burden and the amount of flatness in an individual's retinal ganglion cell layer, to prevent, treat and / or alleviate the effects of an eye disease, to diagnose an eye disease and a predisposition to an eye disease, to monitor eye disease, to predict a patient's responsiveness, and to retain or decrease eye pressure in an individual's eyes

pharmaceutical composition, and methods for reducing plaque burden and the amount of flatness in an individual's retinal ganglion cell layer, to prevent, treat and / or alleviate the effects of an eye disease, to diagnose an eye disease and a predisposition to an eye disease, to monitor eye disease, to predict a patient's responsiveness, and to retain or decrease eye pressure in an individual's eyes

机译：减轻眼底神经节细胞层中斑块负担和扁平度的药物组合物和方法，以预防，治疗和/或减轻眼部疾病的影响，诊断眼部疾病和眼部疾病的易感性，监视眼部疾病，预测患者的反应能力，并保持或降低个体眼睛的眼压

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摘要

The present invention provides novel methods and compositions comprising highly specific and highly effective antibodies that specifically recognize and bind to specific epitopes from a range of -amyloid proteins. The antibodies of the present invention are particularly useful for the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system, particularly associated with amyloid-beta-related pathological abnormalities/changes in the tissues of the visual system.

机译：本发明提供了新颖的方法和组合物，其包含高度特异性和高效的抗体，所述抗体特异性识别并结合来自一系列淀粉状蛋白的特定表位。本发明的抗体特别可用于治疗与视觉系统的组织中的病理异常/改变相关的眼部疾病，特别是与淀粉样蛋白相关的视觉系统的组织中的病理学异常/改变相关的眼病。

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公开/公告号BRPI0818621A2

专利类型
公开/公告日2017-05-23

原文格式PDF
申请/专利权人 AC IMMUNE S.A.;GENENTECH INC.;
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申请/专利号BR2008PI18621
发明设计人 ANDREA PFEIFER;ANDREAS MUHS;MARIA PIHLGREN;RYAN WATTS;
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申请日2008-10-03
分类号A61K39/395;A61P25/28;C07K16/18;C12N15/13;
国家 BR
入库时间 2022-08-21 13:39:43

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