首页> 外国专利> compound, compound or a form thereof, methods of inhibiting bmi-1 function and reducing bmi-1 level, uses of the compound, and pharmaceutical compositions for use in treating bmi-1 mediated cancer

compound, compound or a form thereof, methods of inhibiting bmi-1 function and reducing bmi-1 level, uses of the compound, and pharmaceutical compositions for use in treating bmi-1 mediated cancer

机译:化合物,化合物或其形式,抑制bmi-1功能和降低bmi-1水平的方法,该化合物的用途以及用于治疗bmi-1介导的癌症的药物组合物

摘要

Summary compound, compound or a form thereof, methods of inhibiting bmi-1 function and reducing the level of bmi-1, uses of the compound, and pharmaceutical compositions for use in treating bmi-1 mediated cancer are described. of substituted amine-substituted pyrimidine and forms thereof that inhibit b-specific moloney leukemia virus integrating site 1 (bmi-1) integration site protein 1 and methods for their use to inhibit the function of bmi-1 and reduce the level of bmi-1 to treat bmi-1 mediated cancer in this document. 1/1
机译:描述了概述的化合物,化合物或其形式,抑制bmi-1功能和降低bmi-1水平的方法,该化合物的用途以及用于治疗bmi-1介导的癌症的药物组合物。抑制b-特异性单核细胞白血病病毒整合位点1(bmi-1)整合位点蛋白1的取代胺取代的嘧啶及其形式及其抑制bmi-1功能和降低bmi-1水平的方法在本文件中治疗bmi-1介导的癌症。 1/1

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