首页> 外国专利> formulation of colchicine prolonged release as an active ingredient, method for treating and / or preventing cardiovascular disease or inflammatory disease in an individual, process of preparing a colchicine prolonged release tablet and molded and compressed prolonged release therapeutic composition comprising colchicine and excipients combined in a matrix

formulation of colchicine prolonged release as an active ingredient, method for treating and / or preventing cardiovascular disease or inflammatory disease in an individual, process of preparing a colchicine prolonged release tablet and molded and compressed prolonged release therapeutic composition comprising colchicine and excipients combined in a matrix

机译：秋水仙碱缓释制剂作为有效成分的制剂，个体中用于治疗和/或预防心血管疾病或炎性疾病的方法，制备秋水仙碱缓释片剂的方法以及包含基质中结合有秋水仙碱和赋形剂的模压和压缩的缓释治疗组合物

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resumen formulation of colchicine prolonged release as active ingredient, method for treating and / or preventing cardiovascular disease or inflammatory disease in an individual, process of preparing a colchicine prolonged release tablet and molded and sustained release therapeutic composition. Compressed tablets comprising colchicine and excipients combined in a matrix are provided colchicine pharmaceutical compositions for oral administration once daily. The formulations comprise a sustained release component and an optional immediate release component, which compositions may be selectively adjusted, respectively, to release the active ingredient over a predetermined or desired release profile. Also provided is a method of treating or preventing cardiovascular disease and / or inflammatory disease in mammalian patients comprising administering the novel formulations described herein. 1/1

机译：恢复秋水仙碱缓释作为活性成分的制剂，用于治疗和/或预防个体的心血管疾病或炎性疾病的方法，制备秋水仙碱缓释片剂的方法以及模制和缓释治疗组合物。提供了秋水仙碱药物组合物，其包含结合在基质中的秋水仙碱和赋形剂的压制片剂，用于每天口服一次。所述制剂包含持续释放组分和任选的立即释放组分，可以分别选择性地调节所述组合物，以在预定或期望的释放曲线上释放活性成分。还提供了一种在哺乳动物患者中治疗或预防心血管疾病和/或炎性疾病的方法，该方法包括施用本文所述的新型制剂。 1/1

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公开/公告号BR112015026418A2

专利类型
公开/公告日2017-07-25

原文格式PDF
申请/专利权人 MURRAY AND POOLE ENTERPRISES LIMITED;
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申请/专利号BR20151126418
发明设计人 SUSANNE RIEL;
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申请日2014-04-16
分类号A61K9/20;A61P29;A61P35;
国家 BR
入库时间 2022-08-21 13:40:04

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