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methods for treating hypertension, hyperkalaemia, and chronic kidney disease.

机译:治疗高血压,高钾血症和慢性肾脏疾病的方法。

摘要

The present invention generally relates to methods of treating hypertension (HTN) in patients in need thereof wherein the patient optionally further suffers from chronic kidney disease (CKD) or Type II diabetes mellitus (T2DM). The invention also relates to methods of treating hyperkalemia in a patient in need thereof, wherein the patient suffers from CKD, T2DM or HTN and are optionally being treated with an effective amount of a renin-angiotensin-aldosterone system (RAAS) agent. The invention also relates to methods of treating kidney disease in a patient in need thereof, wherein the patient is optionally being treated with an effective amount of a renin-angiotensin-aldosterone system (RAAS) agent. The methods can comprise administering an effective amount of a potassium-binding polymer to the patient to lower the patient's blood pressure and/or increase or stabilize the patient's kidney function.
机译:本发明一般涉及在有需要的患者中治疗高血压(HTN)的方法,其中所述患者任选地进一步患有慢性肾脏疾病(CKD)或II型糖尿病(T2DM)。本发明还涉及在有需要的患者中治疗高钾血症的方法,其中所述患者患有CKD,T2DM或HTN,并且任选地用有效量的肾素-血管紧张素-醛固酮系统(RAAS)剂治疗。本发明还涉及在有需要的患者中治疗肾脏疾病的方法,其中所述患者任选地用有效量的肾素-血管紧张素-醛固酮系统(RAAS)试剂治疗。该方法可以包括向患者施用有效量的钾结合聚合物以降低患者的血压和/或增加或稳定患者的肾功能。

著录项

  • 公开/公告号BR112015007749A2

    专利类型

  • 公开/公告日2017-07-04

    原文格式PDF

  • 申请/专利权人 RELYPSA INC;

    申请/专利号BR20151107749

  • 发明设计人 GERRIT KLAERNER;LANCE BERMAN;

    申请日2013-10-08

  • 分类号A61K31/78;A61K31/7004;A61K33/06;A61P9/12;A61P13/12;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:13

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