首页> 外国专利> Methods of determining sensitivity of tumor cell growth inhibition by an inhibitor of the kinase of EGFR.Identification of a cancer patient who is likely to benefit from treatment with an inhibitor of EFGR, treatment of cancer in a patient.The selection of a therapy for a patient with cancer and determination of overexpression of ERBB2 gene in a cell.

Methods of determining sensitivity of tumor cell growth inhibition by an inhibitor of the kinase of EGFR.Identification of a cancer patient who is likely to benefit from treatment with an inhibitor of EFGR, treatment of cancer in a patient.The selection of a therapy for a patient with cancer and determination of overexpression of ERBB2 gene in a cell.

机译:确定EGFR激酶抑制剂对肿瘤细胞生长抑制敏感性的方法。确定可能受益于EFGR抑制剂治疗的癌症患者,患者的癌症治疗。癌症患者并确定细胞中ERBB2基因过表达。

摘要

The present invention provides methods of predicting response to a cancer therapy based on the methylation status of the ERBB2 gene. One aspect of the invention provides a method of predicting response to an EGFR inhibitor therapy based on the methylation status of the ERBB2 gene.
机译:本发明提供了基于ERBB2基因的甲基化状态预测对癌症疗法的反应的方法。本发明的一个方面提供了一种基于ERBB2基因的甲基化状态预测对EGFR抑制剂疗法的反应的方法。

著录项

  • 公开/公告号BR112014004762A2

    专利类型

  • 公开/公告日2017-06-13

    原文格式PDF

  • 申请/专利权人 GENENTECH INC;

    申请/专利号BR20141104762

  • 发明设计人 DAVID SHAMES;THOMAS JANUARIO;

    申请日2012-08-30

  • 分类号C12Q1/68;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:39

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