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Method for producing medium-chain ω-hydroxy fatty acids, α,ω-dicarboxylic acids, and ω-amino fatty acids from long-chain fatty acids by biotransformation
Method for producing medium-chain ω-hydroxy fatty acids, α,ω-dicarboxylic acids, and ω-amino fatty acids from long-chain fatty acids by biotransformation
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机译：通过生物转化从长链脂肪酸生产中链ω-羟基脂肪酸，α，ω-二羧酸和ω-氨基酸脂肪酸的方法
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摘要
The present invention relates to a transformant which is transformed to express Baeyer-Villiger monooxygenase (BVMO), a method for producing C5-C14 medium-chain ω-hydroxy fatty acids, α,ω-dicarboxylic acids, ω-amino fatty acids, or alcohols from C16-C20 long-chain fatty acids by biotransformation using the transformant, a method for producing a fatty acid derivative having an ester group which is introduced into the chain thereof from keto fatty acid using the BVMO, and novel ω-hydroxy fatty acids which are prepared by the method. Degradation products such as C5 to C14 ω-hydroxy fatty acids, α,ω-dicarboxylic acids, ω-amino fatty acids, alcohols can be produced in a large amount from C16 to C20 long-chain fatty acids contained in a medium by biotransformation using a transformant capable of expressing BVMO of the present invention. Therefore, it can be widely used to produce ω-hydroxy fatty acids, α,ω-dicarboxylic acids, ω-amino fatty acids or alcohols in a more safe and economic manner.
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