首页> 外国专利> Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes

Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes

机译:两亲Janus糖树状聚合物的模块合成及其自组装成糖树状聚合物的过程

摘要

The invention concerns compounds of the formula (I) wherein: Y1 and Y2 are independently a monosaccharide or disaccharide; X1 and X2 are independently —(R9—O)m—, —(R10)p—, —O—(R11—O)q—, —R16—O—R17—O— or a covalent bond; Q1 and Q2 are independently a nitrogen-containing heterocycle moiety; Z1 and Z2 are independently —(O—R7)—, —(O—C(═O)—R8)a-, —O—C(═O)—R12—C(=0)-R13—, —O—C(═O)—R14—C(═O)—R15 or a covalent bond; R7-R17 are each independently C1-C6 alkyl; R1-R6 are each independently a linear or branched alkyl group; b, c, d, e, f, and g are 0 or 1, provided b+c+d equals at least 2 and e+f+g equals at least 2; and a, m, p, and q are each an integer from 1-6.; embedded image
机译:本发明涉及式(I)化合物,其中:Y 1 和Y 2 独立地是单糖或二糖; X 1 和X 2 独立地是-(R 9 -O) m -,-(R 10 p -,-O-(R 11 -O) q -,-R 16 < / Sup> -O-R 17 -O-或共价键; Q 1 和Q 2 独立地是含氮杂环部分; Z 1 和Z 2 独立地是-(O-R 7 )-,-(OC(═O)-R 8 )a-,-OC(═O)-R 12 -C(= 0)-R 13 -,-OC (═O)-R 14 -C(═O)-R 15 或共价键; R 7 -R 17 各自独立地为C 1 -C 6 烷基; R 1 -R 6 分别独立地为直链或支链烷基; b,c,d,e,f和g为0或1,前提是b + c + d至少等于2,e + f + g至少等于2; a,m,p和q分别是1-6的整数。 “嵌入式图像”

著录项

  • 公开/公告号US9777034B2

    专利类型

  • 公开/公告日2017-10-03

    原文格式PDF

  • 申请/专利权人 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;

    申请/专利号US201414892044

  • 发明设计人 VIRGIL PERCEC;

    申请日2014-05-21

  • 分类号C07H15/26;C07H17/02;C07H1;

  • 国家 US

  • 入库时间 2022-08-21 13:45:04

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