首页> 外国专利> Nucleic acid element candidate molecule and screening method for screening for nucleic acid element for target analysis using the same

Nucleic acid element candidate molecule and screening method for screening for nucleic acid element for target analysis using the same

机译:核酸候选分子和使用该核酸候选分子筛选用于靶标分析的核酸元素的筛选方法

摘要

The present invention provides a novel nucleic acid element candidate molecule for use in screening for a nucleic acid element for target analysis and a novel screening method for screening for a nucleic acid element for target analysis using the same. The candidate molecule according to the present invention is a molecule for screening for a nucleic acid element for target analysis, being the following single-stranded nucleic acid (I): (I) a single-stranded nucleic acid comprising a catalyst sequence (D), a blocking sequence (B), and a binding sequence (A) that binds to a target, linked in this order. The blocking sequence (B) is complementary to a partial region (Dp) in the catalyst sequence (D). A terminal region (Ab) on the blocking sequence (B) side in the binding sequence (A) is complementary to a flanking region (Df) of the partial region (Dp) in the catalyst sequence (D) and is complementary to a terminal region (Af) on the side opposite to the blocking sequence (B) side in the binding sequence (A).
机译:本发明提供了用于筛选用于靶标分析的核酸元件的新型核酸元件候选分子,以及使用其筛选用于靶标分析的核酸元件的新型筛选方法。根据本发明的候选分子是用于筛选用于靶标分析的核酸元件的分子,其是以下单链核酸(I):(I)包含催化剂序列(D)的单链核酸。 ,阻断序列(B)和与靶标结合的结合序列(A)以该顺序连接。封闭序列(B)与催化剂序列(D)中的部分区域(Dp)互补。结合序列(A)中封闭序列(B)侧的末端区域(Ab)与催化剂序列(D)中部分区域(Dp)的侧翼区域(Df)互补,并且与末端互补结合序列(A)中与阻断序列(B)相反的一侧的区域(Af)。

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