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Method for preparing aqueous extract of Ashwagandha leaf with enhanced anticancer activity by using cyclodextrin, and pharmaceutical composition comprising Ashwagandha leaf

机译:利用环糊精制备具有增强的抗癌活性的非洲醉茄叶水提取物的方法以及包含非洲醉茄叶的药物组合物

摘要

It is an object of the present invention to provide a method for preparing an aqueous extract of Ashwagandha leaves, which increases the contents of active ingredients withanone and Witherin A in the aqueous extract of Ashwagandha leaves. Another object of the present invention is to provide a pharmaceutical composition containing Ashwagandha leaves more economically and simply. The present invention relates to a method for preparing an aqueous extract of Ashwagandha leaves, which comprises extracting Ashwagandha leaves in the presence of cyclodextrin, and a method for enhancing the anticancer activity of the aqueous extract of Ashwagandha leaves. The present invention also relates to a pharmaceutical composition for treating or preventing cancer comprising an aqueous extract of Ashwagandha leaves. The present invention also relates to a pharmaceutical composition comprising a dry powder of Ashwagandha leaves and a cyclodextrin.
机译:本发明的一个目的是提供一种制备Ashwagandha叶子的水提取物的方法,其增加了Ashwagandha叶子的水提取物中的活性成分withanone和Witherin A的含量。本发明的另一个目的是提供一种更经济和更简单地包含Ashwagandha叶的药物组合物。本发明涉及一种制备Ashwagandha叶水提物的方法,该方法包括在环糊精存在下提取Ashwagandha叶,以及增强Ashwagandha叶水提物的抗癌活性的方法。本发明还涉及用于治疗或预防癌症的药物组合物,其包含Ashwagandha叶的水提取物。本发明还涉及一种药物组合物,其包含Ashwagandha叶的干粉和环糊精。

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