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Composition for treatment of diabetes comprising sustained insulin analogue conjugate and sustained insulin secretory peptide conjugate
Composition for treatment of diabetes comprising sustained insulin analogue conjugate and sustained insulin secretory peptide conjugate
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机译：包含持续胰岛素类似物结合物和持续胰岛素分泌肽结合物的糖尿病治疗组合物
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摘要
The present invention relates to a pharmaceutical composition for preventing or treating diabetes comprising a continuous insulin analogue and a continuous insulin secretory peptide conjugate, and a method for treating diabetes, more specifically, the pharmaceutical composition comprises: Concomitant administration of a continuous analog conjugate and a continuous insulin secretory peptide conjugate suppresses weight gain associated with insulin administration, suppresses nausea and vomiting associated with insulin secretory peptide administration, lowers insulin dose, and compliance Can be greatly improved. The present invention also provides a pharmaceutical composition for improving pancreatic β-cell side effects in diabetic patients, comprising a long-acting insulin analog conjugate and a long-acting insulin-secreting peptide conjugate, and a step of administering the pharmaceutical composition In particular, there are side effects such as abnormal pancreatic β-cell function, pancreatic β-cell depletion, lipotoxicity, and glucotocity due to progression of diabetes. It is characterized by improving. [Selection] Figure 1
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