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Composition, method and kit for diagnosis of pancreatic / gastrointestinal neuroendocrine neoplasm
Composition, method and kit for diagnosis of pancreatic / gastrointestinal neuroendocrine neoplasm
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机译:诊断胰腺/胃肠道神经内分泌肿瘤的组合物,方法和试剂盒
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摘要
Method for diagnosing, detecting or prognosing GEP-NEN based on the expression level score of a biomarker that exhibits differential expression in a subject with GEP-NEN compared to a reference or control sample I will provide a. The present invention also includes compositions and kits comprising these biomarkers, and methods of using these biomarkers in subsets or panels thereof to diagnose, classify, and monitor the types of GEP-NEN and GEP-NEN. provide. The methods and compositions provided herein are for distinguishing between different stages of GEP-NEN, such as stable GEP-NEN or progressive GEP-NEN, in order to diagnose or classify a subject as having GEPEN. It can also be used to obtain a measure of the risk of developing advanced GEP-NEN and to determine the completeness of treatment of GEP-NEN, including but not limited to surgery and somatostatin therapy.
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