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NOVEL MOLECULARLY TARGETED DRUG FOR THE TREATMENT OF MALIGNANT TUMORS
NOVEL MOLECULARLY TARGETED DRUG FOR THE TREATMENT OF MALIGNANT TUMORS
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机译：新型分子靶向药物治疗恶性肿瘤
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摘要
PROBLEM TO BE SOLVED: To provide a novel molecularly targeted drug targeting a ribosomal protein, RPL29, whose expression is enhanced in malignant tumor cells, and also provide an antitumor drug related to the molecular targeting drug targeting RPL29 and acts more effectively on RPL29.SOLUTION: According to the present invention, there is provided a molecularly targeted drug consisting of antibody or peptide vaccine against RPL29. The molecularly targeted drug targets a portion comprising at least five amino acid residues, which is selected from, among amino acid sequences that constitute RPL29 protein, an amino acid sequence set forth in SEQ ID No.1 in the Sequence Listing or an amino acid sequence where one or more amino acid residues of the amino acid sequence set forth in SEQ ID No.1 are deleted, substituted, introduced, or added.SELECTED DRAWING: Figure 3
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机译：要解决的问题：提供一种靶向核糖体蛋白RPL29的新型分子靶向药物，其在恶性肿瘤细胞中的表达增强，还提供与靶向RPL29的分子靶向药物有关的抗肿瘤药物，并更有效地作用于RPL29。 ：根据本发明，提供了一种由针对RPL29的抗体或肽疫苗组成的分子靶向药物。分子靶向药物靶向包含至少五个氨基酸残基的部分，该氨基酸残基选自构成RPL29蛋白的氨基酸序列，序列表中SEQ ID No.1所示的氨基酸序列或氨基酸序列。其中删除，取代，引入或添加了SEQ ID No.1所示氨基酸序列的一个或多个氨基酸残基。图3
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