PROBLEM TO BE SOLVED: To obtain formulations that promote productions of Kallikrein related peptidase, LEKTI, and SLPI, normalize Corneodesmosome degradation, and normalize keratinization, such as a horny layer thickening or inhibition of turnover delay.SOLUTION: By using one or more extracts selected from Rosae fructus, Artemisia princeps, and black tea as an active ingredient, formulations that promote productions of kallikrein related peptidase, LEKTI, and SLPI, normalize Corneodesmosome degradation, and by extension normalize keratinization can be obtained.SELECTED DRAWING: Figure 1
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