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SLEEP DISORDER MODEL NONHUMAN ANIMAL, ANIMAL CELL FOR SLEEP DISORDER EVALUATION, AND SCREENING METHOD USING THEM

机译：睡眠障碍模型非人类动物，用于睡眠障碍评估的动物细胞以及使用它们的筛选方法

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摘要

PROBLEM TO BE SOLVED: To provide a sleep disorder model nonhuman animal taking on a stable phenotype that can be manufactured easily.;SOLUTION: A sleep disorder model nonhuman animal is characterized in that all or part of functions of a gene related to Ca²⁺-dependent hyperpolarization/depolarization pathway are deficient. An animal cell for sleep disorder evaluation is characterized in that all or part of functions of a gene related to Ca²⁺-dependent hyperpolarization/depolarization pathway are deficient.;SELECTED DRAWING: None;COPYRIGHT: (C)2017,JPO&INPIT

机译：解决的问题：提供具有易于制造的稳定表型的睡眠障碍模型非人类动物;解决方案：睡眠障碍模型非人类动物的特征在于与Ca 2 + 依赖的超极化/去极化途径不足。用于睡眠障碍评估的动物细胞的特征在于与Ca ^{2 + 依赖的超极化/去极化途径相关的基因的全部或部分功能不足。;部分制图：无;版权：（C ）2017，JPO＆INPIT}

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公开/公告号JP2017158528A

专利类型
公开/公告日2017-09-14

原文格式PDF
申请/专利权人 UNIV OF TOKYO;
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申请/专利号JP20160049014
发明设计人 TATSUKI FUMIYA;SUNAGAWA GENSHIRO;SHI SHOI;UEDA YASUKI;
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申请日2016-03-11
分类号A01K67/027;C12N5/10;C12Q1/02;C12N15/09;G01N33/50;G01N33/15;
国家 JP
入库时间 2022-08-21 14:02:03

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