首页> 外国专利> METHOD OF EVALUATING GLIOBLASTOMA MULTIFORME PATIENT APPLICABLE TO IMMUNOTHERAPY TREATMENT BASED ON DENDRITIC CELL TUMOR VACCINES AND METHOD OF PROGNOSTICATING SURVIVAL RATE IN GLIOBLASTOMA MULTIFORME PATIENT AFTER TREATMENT

METHOD OF EVALUATING GLIOBLASTOMA MULTIFORME PATIENT APPLICABLE TO IMMUNOTHERAPY TREATMENT BASED ON DENDRITIC CELL TUMOR VACCINES AND METHOD OF PROGNOSTICATING SURVIVAL RATE IN GLIOBLASTOMA MULTIFORME PATIENT AFTER TREATMENT

机译:基于树突状细胞瘤疫苗的可用于免疫治疗的多形胶质瘤患者评估方法和治疗后多形性胶质瘤患者存活率的预测方法

摘要

A method of evaluating if a glioblastoma multiforme (GBM) patient is applicable to be treated with an immunotherapy based on dendritic cell tumor vaccines includes a sample obtaining step to obtain a sample from the GBM patient, a detecting step to detect an expression level of a biomarker, and a comparing step to compare the expression level of the biomarker to a threshold, wherein the GBM patient is applicable to treat with the immunotherapy based on dendritic cell tumor vaccines when the expression level of the biomarker is lower than the threshold. A method of prognosticating a survival rate in the GBM patient after a treatment includes a sample obtaining step, a detecting step, and a comparing step, wherein the GBM patient is determined to have a good prognosis after the treatment when the expression level of the sample from the GBM is lower than the threshold.
机译:一种评估多形性胶质母细胞瘤(GBM)患者是否适用于基于树突状细胞瘤疫苗的免疫疗法进行治疗的方法,该方法包括:样品获取步骤,用于从GBM患者中获取样品;检测步骤,用于检测树突​​状细胞瘤的表达水平。生物标志物,以及将生物标志物的表达水平与阈值进行比较的比较步骤,其中当生物标志物的表达水平低于阈值时,GBM患者适用于基于树突状细胞瘤疫苗的免疫治疗。在治疗后对GBM患者的存活率进行预后的方法包括样品获取步骤,检测步骤和比较步骤,其中当样品的表达水平确定为GBM患者在治疗后预后良好来自GBM的阈值低于阈值。

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