首页>
外国专利>
PRODUCTION METHODS OF FUNCTIONAL CELL-DERIVED MEMBRANE VESICLES USING MEMBRANE FUSOGENIC LIPOSOMES INCLUDING FUNCTIONALIZED PHOSPHOLIPIDS AND FUNCTIONAL CELL-DERIVED MEMBRANE VESICLES PRODUCING THERETO
PRODUCTION METHODS OF FUNCTIONAL CELL-DERIVED MEMBRANE VESICLES USING MEMBRANE FUSOGENIC LIPOSOMES INCLUDING FUNCTIONALIZED PHOSPHOLIPIDS AND FUNCTIONAL CELL-DERIVED MEMBRANE VESICLES PRODUCING THERETO
展开▼
机译：使用功能性磷脂和功能性细胞膜囊泡的膜融合型脂质体生产功能性细胞膜囊泡的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to a producing method of functional cell membrane-derived vesicles using membrane fusogenic liposomes comprising functional phospholipids, and functional cell membrane-derived vesicles produced from the same. Among various phospholipids, DPhPE is most effectively delivered to cell membrane-derived vesicles, which are secreted by cells treated with membrane fusogenic liposomes, and is confirmed to express a form of functional cell membrane-derived vesicles similar to common cell membrane-derived vesicles. Therefore, the functional cell membrane-derived vesicles manufactured using membrane fusogenic liposomes and formed by conjugating the phospholipid to various functional ingredients such as hydrophilic drugs, MRI contrast agents, and azide groups can be usefully applied to a surface modification of cell membrane-derived vesicles using drug delivering carriers, MRI contrast agents, and click chemistry.
展开▼
