首页> 外国专利> AGENT FOR INHIBITING OR IMPROVING DECREASE OF LORICRIN, TRANSGLUTAMINASE-3 ACTIVATOR, AND AGENT FOR PROMOTING FORMATION OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE OR FOR STRENGTHENING STRUCTURE OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE

AGENT FOR INHIBITING OR IMPROVING DECREASE OF LORICRIN, TRANSGLUTAMINASE-3 ACTIVATOR, AND AGENT FOR PROMOTING FORMATION OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE OR FOR STRENGTHENING STRUCTURE OF SKIN HORNY CELL LAYER CORNIFIED ENVELOPE

机译：抑制或改善Loricrin，Transglutaminease-3激活剂减少的代理商，以及促进皮肤角质层层形成包膜的形成或增强皮肤角质层层周围包膜的结构的代理商

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摘要

The present invention relates to: an agent for inhibiting or improving the decrease of loricrin in a cornified envelope of a horny cell layer of the skin, a transglutaminase-3 activator, and an agent for promoting the formation of a cornified envelope of a horny cell layer of the skin or for strengthening the structure of a cornified envelope of a horny cell layer of the skin, each of which contains sphingomyelin as an active ingredient; a composition; and a food or beverage. According to the present invention, it becomes possible to inhibit or improve the decrease of loricrin in a cornified envelope of a horny cell layer of the skin, and it also becomes possible to activate transglutaminase-3 in a cornified envelope of a horny cell layer of the skin. Therefore, it becomes possible to promote the formation of a cornified envelope of a horny cell layer of the skin and strengthen the structure of a cornified envelope of a horny cell layer of the skin. Due to these effects, the deterioration of a barrier function of skin can be prevented, inhibited or improved in a safe, simple and economically advantageous manner.

机译：本发明涉及：抑制或改善皮肤的角质细胞层的角质包膜中的loricrin减少剂，转谷氨酰胺酶3活化剂和促进角质细胞的角质包膜形成的剂。皮肤层或用于增强皮肤角质细胞层的角质化包膜的结构的层，每个层均含有鞘磷脂作为有效成分;组成;还有食物或饮料根据本发明，可以抑制或改善皮肤的角质细胞层的角质化包膜中的洛瑞克林的减少，并且还可以活化皮肤角质细胞层的角质化包膜中的转谷氨酰胺酶3。皮肤。因此，可以促进皮肤的角质细胞层的角质化包膜的形成，并且可以增强皮肤的角质细胞层的角质化包膜的结构。由于这些作用，可以以安全，简单和经济上有利的方式防止，抑制或改善皮肤的屏障功能。

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公开/公告号WO2016104665A1

专利类型
公开/公告日2016-06-30

原文格式PDF
申请/专利权人 MEIJI CO. LTD.;
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申请/专利号WO2015JP86155
发明设计人 OHBA CHISATO;MORIFUJI MASASHI;ICHIKAWA SATOMI;KAWAHATA KEIKO;
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申请日2015-12-25
分类号A61K31/688;A23L33/10;A61P3/02;A61P17;A61P17/12;A61P17/16;A61P43;
国家 WO
入库时间 2022-08-21 14:17:20

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