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A DNA methylation and genotype specific biomarker of suicide attempt and/or suicide ideation
A DNA methylation and genotype specific biomarker of suicide attempt and/or suicide ideation
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机译:自杀未遂和/或自杀意念的DNA甲基化和基因型特异性生物标志物
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摘要
The present invention relates to the field of biomarkers. More specifically, the present invention relates to the use of biomarkers to predict suicide ideation and/or suicide attempt. In one embodiment, a method for predicting suicide ideation and/or attempt by a subject comprises the steps of (a) measuring the DNA methylation level of a CpG dinucleotide in the 3' untranslated region of SKA2; (b) identifying the genotype at a SNP within the 3' UTR of SKA2, and (c) predicting suicide ideation and/or attempt by the subject using a prediction algorithm.
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