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GENETIC MARKERS AND METHODS FOR IMPROVING DAIRY PRODUCTIVITY AND FITNESS TRAITS

机译:改善乳制品生产力和适宜性状的遗传标记和方法

摘要

The present invention provides methods for improving desirable animal traits including improved fitness and productivity in dairy animals. Also provided are methods for determining a dairy animal's genotype with respect to multiple markers associated with milk production, somatic cell score, daughter pregnancy rate, productive life, and/or net merit. The invention also provides methods for selecting or allocating animals for predetermined uses such as progeny testing or nucleus herd breeding, for picking potential parent animals for breeding, and for producing improved progeny animals. Also provided are methods for identifying genes and/or genetic markers for traits including fitness and productivity traits; including identifying markers that are in allelic association with the SNPs disclosed herein and for identifying the genotypes of a causative mutation underlying a quantitative trait locus (QTL). The invention further provides methods for genotyping animals for multiple SNPs associated with the traits described above.
机译:本发明提供了用于改善期望的动物性状的方法,包括改善了乳类动物的适应性和生产率。还提供了用于确定与牛奶生产,体细胞评分,女儿怀孕率,生产寿命和/或净值相关的多个标志物的奶牛动物基因型的方法。本发明还提供了用于选择或分配用于预定用途的动物的方法,该预定用途诸如后代测试或核群繁殖,用于挑选潜在的亲本动物进行繁殖,以及产生改良的后代动物。还提供了用于鉴定包括适应性和生产力性状在内的性状的基因和/或遗传标记的方法;包括与本文公开的SNP等位基因相关的鉴定标志物,以及用于鉴定定量性状基因座(QTL)基础致病突变的基因型。本发明进一步提供了对动物进行与上述性状相关的多个SNP的基因分型的方法。

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