首页> 外国专利> VACCINE BIOLOGICAL MANUFACTURED FROM MICRO VESICLES (MVS) OF MANNHEIMIA HAEMOLYTICA SEROTYPE A2 OF INTRANASAL APPLICATION IN SHEEP.

VACCINE BIOLOGICAL MANUFACTURED FROM MICRO VESICLES (MVS) OF MANNHEIMIA HAEMOLYTICA SEROTYPE A2 OF INTRANASAL APPLICATION IN SHEEP.

机译:羊膜内应用A2型嗜血杆菌的微囊(MVS)制备的疫苗生物。

摘要

The pneumonic Mannheimiosis (Pasteurellosis) is a disease that affects ruminants in general, in cattle being a persistent and defiant problem. Nowadays, the disease has not been controlled nor prevented, since an effective biological has not been obtained. Mannheimia haemolytica is the main microbial agent associated with the development of this disease. The present invention refers to a vaccine biological, which comprises bacterium micro vesicles (MVs) isolated from a pathogen serotype A2, so as to prove the capacity thereof to awaken a suitable humoral immune response for preventing the individuals exposed to the field strains from developing pathological processes typical of the disease.
机译:肺曼氏病(Pasteurellosis)是一种普遍影响反刍动物的疾病,牛是一个持续存在的挑战性问题。如今,由于尚未获得有效的生物学手段,因此该疾病尚未得到控制或预防。溶血曼海姆氏菌是与该疾病发展相关的主要微生物。本发明涉及一种生物疫苗,其包含从病原体血清型A2分离的细菌微囊泡(MV),以证明其唤醒适当的体液免疫反应的能力,以防止暴露于野外菌株的个体发展为病理性这种疾病的典型过程。

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