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THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

机译：秘书长代表的美利坚合众国卫生和人类服务部

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124Disclosed are inhibitors of the farnesoid X receptor for example of formula (I) wherein R R R X Y Z m and n are as defined herein which are useful in treating or preventing obesity type 2 diabetes/insulin resistance and non alcoholic fatty liver disease in a mammal in need thereof. Also disclosed is a composition comprising a pharmaceutically suitable carrier and at least one compound of the invention a method of method of inhibiting a farnesoid X receptor in a mammal and a method of treating or preventing obesity in a mammal.

机译：124公开了例如式（I）的法尼醇X受体的抑制剂，其中RRRXYZ m和n如本文所定义，可用于治疗或预防需要其的哺乳动物的2型肥胖症糖尿病/胰岛素抵抗和非酒精性脂肪肝疾病。还公开了包含药学上合适的载体和至少一种本发明的化合物的组合物，在哺乳动物中抑制法呢类X受体的方法的方法以及在哺乳动物中治疗或预防肥胖的方法。

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公开/公告号IN201647006033A

专利类型
公开/公告日2016-07-15

原文格式PDF
申请/专利权人
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申请/专利号IN201647006033
发明设计人 PATTERSON ANDREW D;XIE CEN;LI FEI;AMIN SHANTU;JIANG CHANGTAO;GONZALEZ FRANK J;MITCHELL JAMES B;DESAI DHIMANT;
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申请日2016-02-22
分类号C07J9/00;
国家 IN
入库时间 2022-08-21 14:24:36

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